Neonatologie
2009
Halliday HL, Speer CP (2009): Bengt Robertson (1935 – 2008): A Pioneer and Leader in Surfactant Research. Neonatology 95:VI-VIII
Kramer BW, Ladenburger A, Kunzmann S, Speer CP, Been JV, Freek v. Iwaarden J, Zimmermann LIJ, Gantert M, Garnier Y (2009): Intra-venous LPS induced pulmonary maturation and structural changes in fetal sheep. Am J Obstetrics and Gynecology 200(2): 195.e1-10
Kranke P, Schelling P, Frambach T, Wirbelauer J (2009): Remifentanil zur geburtshilflichen Analgesie: eine echte Alternative zum Epiduralkatheter? Anasthesiol Intensivmed Notfallmed Schmerzther 44(10):660-663.
Speer CP (2009): Chorioamniotitis, postnatal factors and proinflammatory response in the pathogenetic sequence of bronchopulmonary dysplasia. Neonatology 95:353-61
Speer CP, Herting E (2009): Prof. Bengt Robertson, Stockholm – Nachruf.
Z Geburtsh Neonatol 213:117
Thomas W (2009): Muttermilchikterus. Pädiatr Praxis 73:286-288
Thomas W, Seidenspinner S, Kawczynska-Leda N, Chmielnicka-Kopaczyk M, Marx A, Wirbelauer J, Szymankiewicz M, Speer CP (2009): Clara Cell Secretory Protein in Tracheobronchial Aspirates and Umbilical Cord Serum of Extremely Premature Infants with Systemic Inflammation. Neonatology 97:228-234
Thomas W, Seidenspinner S, Kramer BW, Kawczynska-Leda N, Chmielnicka-Kopaczyk M, Marx A, Wirbelauer J, Szymankiewicz M, Speer CP (2009): Airway concentrations of angiopoietin-1 and endostatin in ventilated extremely premature infants are decreased after funisitis and unbalanced with bronchopulmonary dysplasia/death. Pediatr Res 65:468-473
Wirbelauer J, Bauer J, Akintürk H (2009): Successful surgery and long time outcome of a critical isthmic coarctation in a 545g extremely preterm infant. Ped Cardio 30(7):1009-1011.
Wirbelauer J, Thomas W, Speer CP (2009): Früh- und Neugeborene mit einem Acute Respiratory Distress Syndrome (ARDS): welche Rolle spielt die Surfactantsubstitution? Z Geburtsh Neonatol 213(2): 33-41.
Wirbelauer J, Speer CP (2009): The role of surfactant treatment in preterm infants and term newborns with acute respiratory distress syndrome (ARDS). J Perinatol. 29 (S2): 18-22.
Wohlleben M, Schweitzer T, Thomas W, Wirbelauer J (2009): Riesige intrakranielle zystische Raumforderung des Säuglings. Monatsschrift Kinderheilkd, epub ahead of print.
2008
Argyriou L, Wirbelauer J, Dev A, Panchulidze I, Shoukier M, Teske U, Nayernia K (2008): A newborn with hereditary haemorrhagic telangiectasia and an unusually severe phenotype.
Swiss Med Wkly 138:432-5
Been JV, Kramer BW, Zimmermann LJ (2008): In utero and early-life conditions and adult health and disease.
N Engl J Med 359:1523-4
Haumont D, Curstedt T, Halliday HL, Robertson B, Saugstad OD, Speer CP (2008): Preface.
Neonatology 93:282-3
Hillman NH, Moss TJ, Nitsos I, Kramer BW, Bachurski CJ, Ikegami M, Jobe AH, Kallapur SG (2008): Toll-like receptors and agonist responses in the developing fetal sheep lung.
Pediatr Res 63:388-93
Jobe AH, Hilman N, Polglase G, Kramer BW, Kallapur S, Pilow J (2008): Injury and inflammation from resuscitation of the preterm infant.
Neonatalogy 94:190-6
Kawcyńska-Leda N, Szymankiewicz M, Chmielnicka-Kopaczyk M, Thomas W, Seidenspinner S, Gadzinowski J(2008): Macrophage migration inhibitory factor (MIF) in very low birth weight infants (VLBW) with intraamniotic infection.
Postępy Neonatologii (Advances in Neonatology) 2:78-83
Kramer BW (2008): Antenatal inflammation and lung injury: prenatal origin of neonatal disease.
J Perinatol 28:S21-7
Kramer BW, Albertine KH, Moss TJM, Nitsos I, Speer CP, Newnham JP, Jobe AH (2008): All-trans retinoic acid does not modulate intra-amniotic endotoxin mediated effects on the fetal sheep lung.
Anat Rec 291:1271-7
Kunzmann S, Seher A, Kramer BW, Wagemanns R, Schütze N, Jakob F, Sebald W, Speer CP (2008): Connective tissue growth factor (CTGF) does not affect TGF-β1 induced Smad3 phosphorylation and T lymphocytes proliferation inhibition.
Int Arch Allergy Immunol. 147:152-60
Polglase GR, Hillman N, Pillow JJ, Cheah F-C, Nitsos I; Moss TJM, Kramer BW, Ikegami M, Kallapur SG, Jobe AH (2008): Positive end-expiratory pressure and tidal volume during initial ventilation of preterm lambs.
Pediatr Res 64:517-22
Speer CP, Halliday HL (2008): Ola Didrik Saugstad – an oxygen radical.
Neonatology 94:188-9
Sweet DG, Huggett MT, Warner JA, Moss TJ, Kloosterboer N, Halliday HL, Newnham JP, Kallapur SG, Jobe AH, Kramer BW (2008): Maternal betamethasone and chorioamnionitis induce different collagenases during lung maturation in fetal sheep.
Neonatology 94:79-86
Thomas W, Speer CP (2008): Non-ventilatory strategies for prevention and treatment of bronchopulmonary dysplasia – what is the evidence?
Neonatology, 94:150-9
Thomas W, Seidenspinner S, Kawczynska-Leda N, Kramer BW, Chmielnicka-Kopaczyk M, Marx A, Szymankiewicz M, Speer CP (2008): Systemic fetal inflammation and reduced concentrations of macrophage migration inhibitory factor (MIF) in airways of extremely premature infants.
Am J Obstetr Gynecol. 198:64.e1-6
Wirbelauer J, Schmidt B, Klingel K, Cao L, Lang F, Speer CP (2008): Serum and gluccocorticoid inducible kinase in pulmonary tissue of preterm fetuses exposed to chorioamnionitis.
Neonatology 93:257-62
Wirbelauer J, Strotmann J, Kirchhoff A, Darge K, Thomas W (2008): Hypertensive crisis in infancy and childhood.
Klin Padiatr 220: 243-7
Wirbelauer J, Thomas W, Siauw C, Wössner R, Speer CP (2008): Leukämoide Reaktion bei extrem unreifen Frühgeborenen.
Z Geburtsh Neonatol 212:165-9
2007
Beer M, Buchner S, Wirbelauer J, Fuchs J, Machann W, Beissert M, Darge K, Hahn D, Köstler H (2007): MR Imaging and MR Spectroscopy for Characterization of Cardiomyopathies in Adolescents - Preliminary Results.
Rofo 179: 932-7.
Ceteci F, Ceteci S, Karreman C, Kramer BW, Asan E, Götz R, Rapp UR (2007): Disruption of Tumor Cell Adhesion Promotes Angiogenic Switch and Progression to Micrometastasis in RAF-Driven Murine Lung Cancer.
Cell Cancer 12:145-59.
Djakovic A, Rieger L, Wirbelauer J, Kalla J, Dietl J (2007): Severe foetal growth retardation in a patient with uterus bicornis, velamentous insertion and partial placental abruption in the 26th week of gestation - a case report.
Z Geburtsh Neonatol 211:169-73.
Holzhauer S, Sitaru AG, Ebell W, Schindler D, Hanenberg H, Wirbelauer J, Walter U, Grossmann R (2007): Decreased platelet reactivity identified by whole blood flow cytometry in Fanconi anaemia patients.
Thromb Haemost 98:1291-7.
Kallapur SG, Jobe AH, Ball MK, Nitsos I, Moss TJM, Hillman NH, Newnham JP, Kramer BW (2007): Pulmonary and Systemic endotoxin tolerance in preterm fetuses exposed to chorioamnionitis J.
Immunol 179: 8491-9.
Kramer BW, Joshi SN, Newnham JP, Sindelar R, Jobe AH, Kallapur SG (2007): Endotoxin-induced maturation of monocytes in preterm fetal sheep lung.
Am J Physiol 293: L345-53.
Kunzmann S, Schmidt-Weber C, Zingg JM, Azzi A, Kramer BW, Blaser K, Akdis CA, Speer CP (2007): Connective tissue growth factor expression is regulated by histamine in lung fibroblasts: Potential role of histamine in airway remodeling.
J Allergy Clin Immunol 119:1398-407
Ranke MB, Vollmer B, Traunecker R, Wollmann HA, Goelz RR, Seibold-Weiger K, Speer CP, Krägeloh-Mann I (2007): Growth and development are similar in VLBW children born appropriate and small for gestational age: an interim report on 97 preschool children.
J Pediatr Endocrinol Metab 20:1017-26.
Sturm A, Speer CP, Wirbelauer J, Grossmann R (2007): Hirudin treatment for multiple thromboses in a preterm infant with inherited thrombophilia.
Blood Coagul Fibrinolysis 18:381-3.
Sturm A, Speer CP, Grossmann R (2007): Overexpressed platelet integrin alpha(IIb)beta (3) in a Fechtner syndrome patient uneventfully undergoing adenotomy.
Ann Hematol 86:387-8
Sweet D, Bevilacqua G, Carnielli V, Greisen G, Plavka R, Saugstad OD, Simeoni U, Speer CP, Valls-i-Soler A, Halliday HL (2007): European Consensus Guidelines on the Management of Neonatal Respiratory Distress Syndrome.
J Perinat Med 35:175-86
Thomas W, Speer CP (2007): Prevention and treatment of bronchopulmonary dysplasia: Current status and future prospects.
J Perinatol 27:S26-32
Thomas W, Speer CP (2007): Prevention and therapy of bronchopulmonary dysplasia – evidence and clinical practice.
Chinese Journal of Contemporary Pediatrics 9:264-77
Wirbelauer J, Schmidt B, Klingel K, Cao L, Lang F, Speer CP (2007): Serum and glucocorticoid inducible kinase in pulmonary tissue of preterm fetuses exposed to chorioamnionitis.
Neonatology 93:257-62
Wirbelauer J, Strotmann J, Kirchhoff A, Darge K, Thomas W (2007): Die hypertensive Krise im Kindes- und Jugendalter.
Klin Padiatr 219:101
Wirbelauer J, Thomas W, Darge K, Singer D (2007): Zentrale Zyanose und Verdichtungen im Thoraxröntgenbild bei einem Säugling. Diagnose: Früh-symptomatische pulmonale arterio-venöse Malformationen bei Morbus Rendu-Osler-Weber.
Monatsschr Kinderheilkd 155: 789-92
Wirbelauer J, Schmidt B, Klingel K, Cao L, Lang F, Speer CP (2007): Serum and Glucocorticoid inducible Kinase in Pulmonary Tissue of Preterm Fetuses exposed to Chorioamnionitis.
Neonatology 93: 257-62
2006
Apitz C, Wirbelauer J: Circulatory failure due to severe cardiac arrhythmia as a result of hyperkalemia in a very low birth weight infant. Klin Padiatr 2006;218:16-9.
Halliday HL, Speer CP: Lucinactant versus poractant-alpha in premature lambs. Pediatrics 2006;117:2324-5
Halliday HL, Speer CP: Editorial Note. Biol Neonate 2006;90:73
Halliday HL, Speer CP: Editorial Note. Biol Neonate 2006;90:217
Klotz P, Tappe D, Abele-Horn M, Warmuth-Metz M, Sörensen N, Speer CP, Girschick HJ: Cerebral mass in a 13-year-old girl following long-term sojourn in the tropics. J Med Microbiol 2006; 55:345-7
Kramer BW: "Recent advances in neonatal medicine", 6-9 October 2005, Würzburg, Germany. Z Geburtsh Neonatol. 2006;210:25-30
Kunzmann S, Wright JR, Steinhilber W, Kramer BW, Blaser K, Speer CP, Schmidt-Weber C: TGF-beta1 in SP-A preparations influence immune suppressive properties of SP-A on human CD4+ T lymphocytes. Am J Physiol Lung Cell Mol Physiol. 2006;291: L747-56
Kunzmann S, Speer CP, Jobe AH, Kramer BW: Antenatal inflammation induced TGF-beta1 but suppressed CTGF in preterm lungs.Am J Physiol Lung Cell Mol Physiol. 2007; 292:223-31
Maschmann J, Hamprecht K, Weissbrich B, Dietz K, Jahn G, Speer CP: Freeze-thawing of breast milk does not prevent cytomegalovirus transmission to a preterm infant. Arch Dis Child Fetal Neonatal Ed 2006;91:F288-90
Neuberger P, Hamprecht K, Vochem M, Maschmann J, Speer CP, Poets CF, Goelz R: Case control study of symptoms and neonatal outcome of human milk-transmitted cytomegalovirus infection in preterm infants. J Pediatr 2006;148:326-31
Nitsos I, Rees SM, Duncan J, Kramer BW, Harding R, Newnham JP Moss TJM: Chronic exposure to intra-amniotic lipopolysaccharide affects the ovine fetal brain. J. Soc. Gynecol. Investig.2006;13:239-247
Obergfell A, Sturm A, Speer CP, Walter U, Grossmann R: Factor VIII is a positive regulator of platelet function. Platelets 2006; 17:448-53
Schropp C, Speer CP, Schweitzer T, Krauss J: Congenital skin lesions in occult spinal dysraphism – what is typical? Z Geburtsh Neonatol 2006;210:222-7
Siauw C, Kobsar A, Dornieden C, Beyrich C, Schinke B, Schubert-Unkmeir A, Abele-Horn M, Speer CP, Eigenthaler M: Group B streptococcus isolates from septic patients and healthy carriers differentially activate platelet signalling cascades. Thromb Haemost 2006;95:836-49
Speer CP: Pulmonary inflammation and bronchopulmonary dysplasia. J Perinatol 2006;26:S57-62.
Speer CP: Inflammation and Bronchopulmonary Dysplasia: A Continuing Story. Sem Fetal Neonat Med 2006;11:354-62.
Speer CP: Role of inflammation in the pathogenesis of acute and chronic neonatal lung disease. In: The Newborn Lung: Questions and Controversies in Neonatology Series Pulmonary Volume. Bancalari E (Volume Editor). 2006
Speer CP: Role of inflammation in the evolution of bronchopulmonary dysplasia. Drug Discovery Today, Disease Mechanisms 2006;3:409-14
Sturm A, Speer CP, Grossmann R: Overexpressed platelet integrin alpha(IIb)beta (3) in a Fechtner syndrome patient uneventfully undergoing adenotomy. Ann Hematol. 2007
Thomas W, Speer CP: Prevention and treatment of bronchopulmonary dysplasia: Current status and future prospects. J Perinatol 2006
2005
Bartram U, Darge K: Harmonic versus conventional ultrasound imaging of the urinary tract in children. Pediatr Radiol. 2005;35:655-60
Bartram U, Wirbelauer J, Speer CP: Heterotaxy Syndrome - Asplenia and Polysplenia as Indicators of Visceral Malposition and Complex Congenital Heart Disease. Biol Neonate 2005;88:278-90
Curstedt T, Halliday HL, Robertson B, Saugstad OD, Speer CP: Proceedings of the 20th International Workshop on Surfactant Replacement, Belfast, June 2-5, 2005: Preface. Biol Neonate 2005;87:282
D’Alquen D, Kramer BW, Seidenspinner S, Marx A, Berg D, Groneck P, Speer CP: Activation of umbilical cord endothelial cells and fetal inflammatory response in preterm infants with chorioamnionitis and funisitis. Pediatr Res 2005;57:263-9
Fischer M, Schwager K, Wirbelauer J: Atemwegsobstruktionen bei Patienten mit Mukopolysaccharidose: erhöhen diese die Rate perioperativer Komplikationen? Päd Praxis 2005;66:471-80
Groneck P, Speer CP: Medikamentöse Prophylaxe und Therapie der bronchopulmonalen Dysplasie. Z Geburtsh Neonatol 2005;209:119-27
Kallapur SG, Nitsos I, Moss TJ, Kramer BW, Newnham JP, Ikegami M, Jobe AH: Chronic endotoxin exposure does not cause sustained structural abnormalities in the fetal sheep lungs. Am J Physiol Lung Cell Mol Physiol. 2005;288:L966-74.
Koenig C, Hebestreit H, Valenza G, Abele-Horn M, Speer CP: Legionella waltersii – a novel cause of pneumonia? Acta Paediatr 2005;94:1505-7
Kramer BW, Ikegami M, Moss TJ, Nitsos I, Newnham JP, Jobe AH: Endotoxin-induced chorioamnionitis modulates innate immunity of monocytes in preterm sheep. Am J Respir Crit Care Med. 2005;171:73-7.
Kramer BW, Jobe AH: The clever fetus: responding to inflammation to minimize lung injury.
Biol Neonate 2005;88:202-7.
Kramer BW, Kaemmerer U, Kapp M, Herbst D, Marx A, Berg D, Groneck PA, Speer CP: Decreased expression of angiogenic factors in placentas with chorioamnionitis after preterm birth. Pediatr Res 2005;58:607-12
Kunzmann S, Warmuth-Metz M, Girschick HJ: Cerebral demyelination in association with TNF-inhibition therapy in a 5-year-old girl with aseptic meningitis as the first symptom of Still's disease. Scand J Rheumatol 2005;34:76-8.
Kunzmann S, Kullak-Ublick GA, Greiner A, Jeschke R, Hebestreit H: Effective opiate-receptor antagonist therapy of cholestatic pruritus induced by an oral contraceptive.
J Pediatr Gastroenterol Nutr 2005;40:596-9.
Robertson B, Speer CP: Henry L. Halliday – Master of evidence-based neonatology. Biol Neonate 2005;88:246-7
Schmidt-Weber CB, Letarte M, Kunzmann S, Ruckert B, Bernabeu C, Blaser K: TGF-{beta} signaling of human T cells is modulated by the ancillary TGF-{beta} receptor endoglin.
Int Immunol. 2005;17:921-30
Sitaru AG, Holzhauer S, Speer CP, Singer D, Obergfell A, Walter U, Speer CP, Grossmann R: Neonatal platelets: Are they different? Platelets 2005;16:203-210
Sitaru AG, Speer CP, Holzhauer S, Obergfell A, Walter U, Grossmann R: Chorioamnionitis is associated with increased CD40L expression on cord blood platelets. Thromb Haemost 2005;94:1219-23
Thomas W, Speer CP: Management of infants with bronchopulmonary dysplasia in Germany. Early Hum Dev. 2005;81:155-63.
Thomas W, Speer CP: Die Bronchopulmonale Dysplasie Frühgeborener – Epidemiologie, Pathogenese und Therapie. Monatsschr. Kinderheilkd 2005;153:211-9
2004
May M, Ströbel P, Preisshofen T, Seidenspinner S, Marx A, Speer CP (2004): Apoptosis and proliferation in lungs of ventilated and oxygen-treated preterm infants. Eur Respir J 23: 113-121
Bartram U, Speer CP (2004): The role of transforming growth factor Beta in lung development and disease. Chest 125 (2):754-765
Speer CP: Neonatologie. In: Koltzko B (Hsg) (2004): Kinderheilkunde und Jugendmedizin. Springer Verlag, Berlin/Heidelberg/New York 49-116
Bauer K, Groneck P, Speer CP: Intensivmedizin bei Früh- und Neugeborenen. In: Buchardi H, Larsen R, Schuster H-P, Suter PM (Hsg) (2004): Die Intensivmedizin. Springer Verlag, Berlin/Heidelberg/New York 1153-1200
Speer CP: Reanimation des Neugeborenen. In: Reinhardt D (Hsg) (2004): Therapie der Krankheiten im Kindes- und Jugendalter. Springer Verlag, Berlin/Heidelberg/New York 3-13
Speer CP: Neonatales Atemnotsyndrom. In: Reinhardt D (Hsg) (2004): Therapie der Krankheiten im Kindes- und Jugendalter. Springer Verlag, Berlin/Heidelberg/New York 14-19
Wohlfahrt JG, Karagiannidis C, Kunzmann S, Epstein MM, Kempf W, Blaser K, Schmidt-Weber CB (2004): Ephrin-A1 suppresses Th2 cell activation and provides a regulatory link to lung epithelial cells. J Immunol. 172(2): 843-50.
Bartram U, Singer D: Infant botulism and sudden infant death syndrome. Klin Padiatr. 2004;216:26-30.
Bartram U, Speer CP: The role of transforming growth factor beta in lung development and disease. Chest 2004;125:754-65
Fischer M, Wirbelauer J, Hamm H: Schwere arzneimittelinduzierte Hautreaktion: toxische epidermale Nekrolyse durch Carbamazepin. Klin Pädiatr 2004;216:288-293
Cao L, Liu C, Cai B, Jia X, Kang L, Speer CP, Sun B: Nuclear factor-kappa b expression in alveolar macrophages of mechanically ventilated neonates with respiratory distress syndrome. Biol Neonate 2004;86:116-123
Goelz R, Hamprecht K, Vochem M, Maschmann J, Speer CP, Jahn G, Poets CF: Breast feeding of very preterm infants of HCMV-seropositive mothers. Z Geburtsh Neonatol 2004; 208:118-21
Götz R, Kramer BW, Camarero G, Rapp UR: BAG-1 haplo-insufficiency impairs lung tumorigenesis. BMC Cancer. 2004;4:85
Hamprecht K, Maschmann J, Muller D, Dietz K, Besenthal I, Goelz R, Middledorp JM, Speer CP, Jahn G: Cytomegalovirus (CMV) Inactivation in Breast Milk: Reassessment of Pasteurization and Freeze-Thawing. Pediatr Res 2004;56:529-35
König C, Wirbelauer J, Zillikens D, Speer CP: Differential diagnosis of bullous skin lesions in neonates – pemphigoid gestationis. Z Geburtsh Neonatol 2004;208:236-8
Kramer BW, Götz R, Rapp UR: Use of mitogenic cascade blockers for treatment of C-Raf induced lung adenoma in vivo: CI-1040 strongly reduces growth and improves lung structure.
BMC Cancer 2004;4:24
Kramer BW, Ikegami M, Moss TJ, Nitsos I, Newnham JP, Jobe AH: Antenatal betamethasone changes cord blood monocyte responses to endotoxin in preterm lambs.
Pediatr Res 2004;55:764-8
May M, Ströbel P, Preisshofen T, Seidenspinner S, Marx A, Speer CP: Apoptosis and proliferation in lungs of ventilated and oxygen-treated preterm infants. Eur Respir J 2004;23:113-21
May M, Marx A, Seidenspinner S, Speer CP: Apoptosis and proliferation in lungs of human fetuses exposed to chorioamnionitis. Histopathology 2004;45:283-90
Speer CP: Respiratory Distress Syndrome of Preterm Infants: An Inflammatory Disease? Applied Cardiopulmonary Pathophysiology 2004;131: 85-7
Tollofsrud PA, Medbo S, Solas AB, Robertson B, Speer CP, Seidenspinner S, Drevon CA, Saugstad OD: Intratracheal albumin reduces interleukin-8 in tracheobronchial aspirates in piglets after meconium aspiration. J Perinat Med 2004;32:78-83
Urlichs F, Speer CP: Neutrophil Function in Preterm and Term Infants. Neo Reviews, 2004;5:417-29
Vollmer B, Seibold-Weiger K, Schmitz-Salue C, Hamprecht K, Goelz R, Kraegeloh-Mann I, Speer CP: Postnatally acquired cytomegalovirus infection via breast milk: effects on hearing and development in preterm infants. Pediatr Infect Dis J 2004;23:322-7
Wirbelauer J, Singer D, Darge K, Speer CP: Aseptische Meningitis nach intrathekaler Infusion einer parenteralen Ernährungslösung: Beispiele seltener Fehllagen zentraler Venenkatheter bei Frühgeborenen. Z Geburtsh Neonatol 2004;208:63-7
Wirbelauer J, Speer CP: Die Inhalation von Stickstoffmonoxid in der Neonatologie: Stellenwert dieser Therapie im Jahre 2004. Z Geburtsh Neonatol 2004;208:79-90.
Wirbelauer J, Kramer U, Sieverding L: Mycotic aneurysm of the aorta in a patient with coarctation and endothelitis. European Heart Journal 2004;25:Cover.
Wohlfahrt JG, Karagiannidis C, Kunzmann S, Epstein MM, Kempf W, Blaser K, Schmidt-Weber CB: Ephrin-A1 suppresses Th2 cell activation and provides a regulatory link to lung epithelial cells. J Immunol. 2004;172:843-50.
2003
Speer CP (2003): Inflammation and Bronchopulmonary Dysplasia. Semin Neonatol 8: 29-38.
Molin DG, Bartram U, Van der Heiden K, Van Iperen L, Speer CP, Hierck BP, Poelmann RE, Gittenberger-de-Groot AC (2003): Expression patterns of Tgfbeta1-3 associate with myocardialisation of the outflow tract and the development of the epicardium and the fibrous heart skeleton. Dev Dyn. 227(3): 431-444.
Tauscher MK, Berg, D, Brockmann M, Seidenspinner S, Speer CP, Groneck P (2003): Association of histologic chorioamnionitis, increased level of cord blood cytokines, and intracerebral haemorrhage in preterm neonates. Biol Neonate 83: 166-170
Hamprecht K, Witzel S, Maschmann J, Dietz K, Baumeister A, Mikeler E, Goelz R, Speer CP, Jahn G (2003): Rapid detection and quantification of cell free dytomegalovirus by a high-speed centrifugation-based microculture assay: comparison to longitudinally analyzed viral DNA load and pp67 late transcript during lactation. J Clin Virol 28 (3): 303-316
Hamprecht K, Maschmann J, Vochem M, Speer CP, Jahn G: Transmission of cytomegalovirus to preterm infants by breastsfeeding. Monographs in Virology. In: Prösch S, Cinatl J, Scholz M (eds) (2003): New Aspects of CMV-related Immunopathology. Karger, Basel 24: 43-52
Speer CP (2003): Pre- and postnatal inflammatory mechanisms in chronic lung disease of preterm infants. Pediatr Respir Rev 83: 255-258
Kramer BW, Speer CP (2003): Die Surfactantproteine A und D: Wesentliche Faktoren des pulmonalen Abwehrsystems. Z Geburtsh Neonatol 207: 41-47
Tollofsrud PA, Haakonsen P, Drevon CA, Speer CP, Seidenspinner S, Saugstad OD (2003): Comparison of pro inflammatory and pulmonary effects of lipid- and water-soluble components in meconium, in a newborn piglet model. Biol Neonate 84: 330 - 337
Speer CP: Neonatologie. In: Lentze MJ, Schaub J, Schulte FJ, Spranger J (Hsg) (2003): Pädiatrie – Grundlagen und Praxis. Springer Verlag, Berlin/Heidelberg/New York 423-473
Kallapur SG, Kramer BW, Moss TJM, Newnham JP, Jobe AH, Ikegami M, Bachurski CJ (2003) Maternal glucocorticoids increase endotoxin induced lung inflammation in preterm lambs. Am J Physiol 284: L633-L642.
Ikegami M, Moss TJM, Kallapur SG, Mulrooney N, Kramer BW, Nitsos I, Bachurski CJ, Newnham JP, Jobe AH (2003) Minimal lung and systemic responses to TNFa in preterm sheep. Am J Physiol 285: L121-L129.
Kramer BW, Jobe AH, Ikegami M (2003) Monocyte function in preterm, near term and adult sheep. Pediatr Res 54: 52-57.
Newnham JP, Kallapur SG, Kramer BW, Moss TJM, Nitsos I, Ikegami M, Jobe AH (2003) Betamethasone effects on chorioamnionitis induced by intra-amniotic endotoxin in sheep. Am J Obstet Gynecol 189: 1458-1466.
Kramer BW. (2003) "Recent advances in neonatal medicine", 18-20 October 2002, Würzburg, Germany. Z Geburtshilfe Neonatol; 207: 74-76.
Kunzmann S, Wohlfahrt JG, Itoh S, Asao H, Komada M, Akdis CA, Blaser K, Schmidt-Weber CB (2003): SARA and Hgs attenuate susceptibility to TGF-b1-mediated T-cell suppresion. FASEB J 17: 194-202
Kunzmann S, Mantel PY, Wohlfahrt JG, Akdis M, Blaser K, Schmidt-Weber CB (2003): Histamine enhances TGF-b1 mediated suppression of Th2 responses. FASEB J 2003: 1089-95.
Wohlfahrt JG, Kunzmann S, Menz G, Kneist W, Akdis CA, Blaser K, Schmidt-Weber CB (2003): T cell phenotype in allergic asthma and atopic dermatitis. Int Arch Allergy Immunol 131: 272-82.
Tiemessen MM, Kunzmann S, Schmidt-Weber CB, Garssen J, Bruijnzeel-Koomen CA, Knol EF, Van Hoffen E (2003): Transforming growth factor-beta inhibits human antigen-specific CD4+ cell proliferation without modulating the cytokine response. Int Immunol 15: 1495-504.
Singer D (2003): Die schwierige Prognose der Frühgeborenen. Pädiat Prax 63: 8-10
Girschick G, Singer D, Trusen A, Dietl J, Müller T (2003): Intrauterine regression of an adrenal mass. Ultrasound Obstet Gynecol 21: 307-309
Kohlhase J, Liebers M, Backe J, Baumann-Muller A, Bembea M, Destree A, Gattas M, Grussner S, Muller T, Mortier G, Skrypnyk C, Yano S, Wirbelauer J, Michaelis RC (2003): High incidence of the R276X SALL1 mutation in sporadic but not familial Townes-Brocks syndrome and report of the first familial case. J Med Genet 40:e127.
2002
Singer D (2002): Phylogenese des Stoffwechsels der Säugetiere. Anästhesiol. Intensivmed. Notfallmed Schmerzther 37: 441- 460
Singer D (2002): Die perinatale Hirnschädigung als Ausdruck einer erschöpften Hypoxietoleranz. Pädiat Prax 61: 219-222
Singer D, Ince A, Hallmann B (2002): Oxygen supply, body size, and metabolic rate at the beginning of mammalian life. Thermochim Acta 394: 253-259
Shehata-Dieler WE, Dieler R, Wenzel G, Keim R, Singer D, von Deuster C (2002): Das Würzburger Hörscreening-Programm bei Neugeborenen. Erfahrungen bei mehr als 4000 Säuglingen - Einfluss nichtpathologischer Faktoren auf die Messergebnisse. Laryngo-Rhino-Otol 81: 204-210
Meyer-Wentrup F, Speer CP (2002): Neonatale Alloimmunthrombozytopenie mit hämorrhagischer Infarzierung der rechten Hemisphäre. Z Geburtsh Neonatol 206: 26-29
Schmidt-Weber CB, Kunzmann S, Blaser K. (2002): TGF-b-mediated Control of Allergen-specific T-cell Responses. Curr Allergy Asthma Rep 2: 259-262
Groneck P, Speer CP (2002): Chronische Lungenkrankheit oder bronchopulmonale Dysplasie. Monatsschr Kinderheilkd 150; 344-354
Nanan R, Wirbelauer J, Werner E, Schrod L, Speer CP (2002): Angeborene Hyposplenie mit multiplen Begleitfehlbildungen: Variante des Ivemark-Syndroms. Klin Pädiatr 214: 299-302
Hummler HD, Groneck P, Pohlandt F, Speer CP (2002): Vor- und Nachteile einer postnatalen Glukokortikosteroidtherapie bei Frühgeborenen. Monatsschr Kinderheilkd, 150: 710-723
Speer CP (2002): Die Surfactant-Substitutionstherapie: Ein entscheidender Durchbruch in der Behandlung des Atemnotsyndroms Frühgeborener. Monatsschr Kinderheilkd 150: 659-668
Wirbelauer J, Speer CP (2002): Die Bedeutung von inhalativem Stickstoffmonoxid (iNO) für die Behandlung Neugeborener. Monatsschr Kinderheilkd 150: 697-709
Maschmann J, Speer CP, Jahn G, Hamprecht K (2002): Freezing of breast milk does not prevent Cytomegalovirus (CMV) infection in premature infants: a case report and results from spiking experiments. J Matern Fetal Neonatal Med 11 (suppl 1): 110
Groneck P, Speer CP (2002): Die Behandlung der bronchopulmonalen Dysplasie in der kinderärztlichen Praxis. Pädiat. Prax. 60: 453-460
Banerjea MC, Speer CP (2002): Neonatale Sepsis. Pädiat. Prax. 61: 371-382
Banerjea MC, Speer CP (2002): The current role of colony stimulating factors in prevention and treatment of neonatal sepsis. Semin Neonatol 7(4): 335-349
Banerjea MC, Wirbelauer J, Adam P, Trusen A, Marx A, Speer CP (2002): Bilateral cystic adenomatoid lung malformation type III – a rare differential diagnosis of pulmonary hypertension in neonates. J Perinat Med 30: 429-436
Banerjea MC, Wirbelauer J, Trusen A, Speer CP (2002): Bilaterale hypoxisch-ischämische Thalamusläsionen im Neugeborenenalter. Z Geburtsh Neonatol 206: 242-246
Speer CP (2002): Pre- and postnatal inflammatory events in chronic lung disease of preterm infants. Acta Pharmacol Sin 23 Suppl.: 29-32
Speer CP (2002): Clinical experience with the natural porcine surfactant preparation Curosurf. Acta Pharmacol Sin 23 Suppl: 82-122
Halliday HL, Speer CP (2002): Bengt Robertson: A surfactant pioneer. Biol Neonate 82: 272-273
Willet KE, Kramer BW, Kallapur SG, Moss TJ, Newnham JP, Sly PD, Ikegami M, Jobe AH (2002) Intra-amniotic injection of IL-1 induces inflammation and maturation in fetal sheep lung. Am J Physiol 282: L411-L420.
Kramer BW, Ikegami M, Jobe AH (2002) Intratracheal endotoxin induces systemic inflammation in ventilated preterm lambs. Am J Respir Crit Care Med 165:463-469.
Moss TJ, Newnham JP, Willet KE, Kramer BW, Jobe AH, Ikegami M (2002) Intra-amniotic endotoxin at early gestation improves lung function in preterm lambs. Am J Respir Crit Care Med 165: 805-811.
Newnham JP, Moss TJ, Kramer BW, Nitsos I, Ikegami M, Jobe AH (2002) The fetal maturational and inflammatory responses to different routes of endotoxin infusion in sheep. Am J Obstet Gynecol 186: 1062-1068.
Kramer BW, Kramer S, Ikegami M, Jobe AH (2002) Injury, inflammation and remodeling in fetal sheep lung after intraamniotic endotoxin. Am J Physiol 283: L452-L459.
Jobe AH, Kramer BW, Moss TJ, Newnham JP, Ikegami M (2002) Decreased indicators of lung injury with continuous positive expiratory pressure in preterm lambs. Pediatr Res 52: 387-392.
Moss T, Nitsos I, Kramer BW, Ikegami M, Newnham JP, Jobe AH (2002) Intra-amniotic endotoxin induces preterm lung maturation by direct effects on the developing respiratory tract in sheep. Am J Obstet Gynecol 187: 1059-1065.
2001
Speer CP (2001): New insights into the pathogenesis of pulmonary inflammation in preterm infants. Biol Neonate 79: 205-209
Schmidt B, Cao L, Mackensen-Haen S, Kendziorra H, Klingel K, Speer CP (2001): Chorioamnionitis and inflammation of the fetal lung. Am J Obstet Gynecol, 184: 173-7
Strate van der BWA, Harmsen MC, Schäfer P, Swart PJ, The TH, Jahn G, Speer CP, Meijer DKF, Hamprecht K (2001): Viral load and not lactoferrin concentrations in breast milk correlates with the transmission of Human Cytomegalovirus (HCMV) to preterm neonates. Clinic Diagn Laborat Immunol, 8: 818-821
Hamprecht K, Maschmann J, Vochem M, Dietz K, Speer CP, Jahn G (2001): Epidemiology of postnatal mother-to-preterm-child transmission of cytomegalovirus by breastfeeding. Lancet 357: 513-518
Groneck P, Schmale J, Soditt V, Stützer H, Götze-Speer B, Speer CP (2001): Bronchoalveolar inflammation following airway infection in preterm infants with chronic lung disease. Pediatr Pulmonol 31: 1-8
Schrod L, Neuhaus T, Horwitz AE, Speer CP (2001): The effect of dexamethasone on respirator-dependent very-low-birth-weight infants is best predicted by chest X-ray. Pediatr Radiol 31:332-338
Bartram U, Molin DGM, Wisse LJ, Mohammad A, Sanford LP, Doetschman T, Speer CP, Poelmann RE, Gittenberger-de Grott AC (2001): Double-outlet right ventricle and overriding tricuspid valve reflect disturbance of looping, myocardialization, endocardial cushion differentiation, and apoptosis in TGF-b2-knockout mice. Circulation, 103: 2745-2752
Maschmann J, Hamprecht K, Dietz K, Jahn G, Speer CP (2001): Cytomegalovirus infection of extremely low-birth weight infants via breast milk. Clin Infect Disease 33: 1998-2003
Banerjea MC, Speer CP (2001): Bilateral thalamic lesions in a newborn with intrauterine asphyxia after maternal cardiac arrest ? a case report with literature review. J Perinatol 21: 405-409
Saugstad OD, Bevilacqua G, Katona M, Speer CP, Valls-i-Soler A (2001): Surfactant therapy in the Newborn. Prenat Neon Med, 6:56-60
Speer CP: Neonatologie. In: Speer CP, Gahr M (Hrsg) (2001): Pädiatrie. Springer-Verlag Berlin, Heidelberg, New York, 153-239
Kramer, B.W., Jobe, A.H., Bachurski, C.J., Ikegami, M. (2001). Surfactant protein A recruits neutrophil granulocytes into the lungs of ventilated preterm sheep. Am. J. Respir. Crit. Care Med. 163: 158-165.
Bachurski, C.J., Ross, G.F., Ikegami, M., Kramer, B.W., Jobe, A.H. (2001). Intra-amniotic endotoxin increases pulmonary surfactant proteins and induces SP-B processing in fetal sheep. Am. J. Physiol. 280: L279-L285.
Kramer, B.W., Jobe, A.H., Ikegami, M. (2001) Exogenous surfactant changes the phenotype of alveolar macrophages in mice. Am. J. Physiol. 280: L689-L694.
Naik, A.S., Kallapur, S.G., Bachurski, C.J., Jobe, A.H., Michna, J., Kramer, B.W., Ikegami, M. (2001) Effects of ventilation with different PEEP on cytokine expression in the preterm lamb lung. Am. J. Respir. Crit. Care Med. 164: 494-498.
Kramer, B.W., Moss, T.J., Willet, K.E., Newnham, J.P., Sly, P.D., Kallapur, S.G., Ikegami, M., Jobe, A.H. (2001) Dose and time response after intraamniotic endotoxin in preterm lambs. Am. J. Respir. Crit. Care Med. 164: 982-98
2000
Gerber CE, Bruchelt G, Goetze-Speer B, Speer CP (2000): Detection by ELISA of low transferrin levels in bronchoalveolar secretions of preterm infants. J Immunol Meth 233(1-2): 41-45
Erb MA, Heinemann MK, Wendel HP, Häberle L, Sieverding L, Speer CP, Ziemer G (2000): S-100 after correction of congenital heart defects in neonates: is it a reliable marker for cerebral damage? Ann Thorac Surg 69(5): 1515-1519
Gessler P, Neu S, Borckmann Y, Speer CP (2000): Decreased mRNA expression of G-CSF receptor in cord blood neutrophils of term newborn. Biol Neonate 77: 168-173
Speer CP, Robertson B, Halliday HL (2000): Commentary: Randomized trial comparing natural and synthetic surfactant: Increased infection rate after natural surfactant? Acta Paediatr 89: 510-512 (2000)
Maschmann J, Erb MA, Heinemann MK, Ziemer G, Speer CP (2000): Evaluation of Protein S-100 serum concentrations in healthy newborns and seven newborns with perinatal acidosis. Acta Paediatr 89: 553-555
Feist N, Berger D, Speer CP (2000): Anti-endotoxin antibodies in human milk: correlation with infection of the newborn. Acta Paediatr 89: 1087-92
Seibold-Weiger K, Wollmann HA, Ranke MB, Speer CP (2000): Plasma concentrations of the carboxyterminal propeptide of type I procollagen (PICP) in preterm neonates from birth to term. Pediatr Res 48: 104-108
Speer CP, Groneck P (2000): Inflammatory mediators in neonatal lung disease. In: Bland R, Coalson J (eds) Chronic lung disease in early infancy. Marcel Dekker, New York, Basel, pp 147-157
Singer, D., M. Schröder, K. Harms (2000): Vorteile der wassergefilterten gegenüber herkömmlicher Infrarot-Strahlung in der Neonatologie. Z. Geburtsh. Neonatol. 204, 85-92
Singer, D., in collaboration with F. Bach, U. Zeller, E. Hehenkamp, A. Waldow, W. Schröter, H.-J. Kuhn (2000): From hibernators to neonates: a comparative-physiological approach to metabolic reduction. In: Forschung und Klinik an der Schwelle zum 3. Jahrtausend (Publikationen der Jung-Stiftung für Wissenschaft und Forschung, Bd. 9), hrsg. v. Siegenthaler, W., R. Haas; Thieme, Stuttgart, S. 222-233
Singer, D. (2000): Überleben im Kältestress: Biologische Regelmechanismen der Körpertemperatur.In: Unterkühlung im Rettungsdienst, hrsg. von Turner, E., G. Kaudasch; Pabst Science Publishers, Lengerich, S. 49-53
Singer, D. (2000): Thermoregulation. In: Malignant hyperthermia, ed. by Schulte am Esch, J., J. Scholz, F. Wappler; Pabst Science Publishers, Lengerich, pp. 78-90
Kramer, B.W., Martin, T., Henn, W., Lal, S., Speer, C.P. (2000). Lung hypoplasia in a patient with del(2)(q33-q35) demonstrated by chromosome microdissection. Am. J. Med. Genet. 84: 184-188.
Kramer, B.W., Ikegami, M., Jobe, A.H. (2000). Surfactant phospholipid catabolic rate is pool size dependent in mice. Am. J. Physiol. 279: L842-L848.
1999
Groneck P, Goetze-Speer B, Speer CP (1999) : Effects of inhaled beclomethasone compared to systemic dexamethasone on lung inflammation in preterm infants at risk of chronic lung disease. Pediatr Pulmonol 27: 383-387
Speer CP (1999): Inflammatory mechanisms in neonatal chronic lung disease. Eur J Pediatr 158(Suppl 1): S18-S22
Gerber CE, Bruchelt G, Stegmann H, Schweinsberg F, Speer CP (1999) : Presence of bleomycin-detectable free iron in the alveolar system of preterm infants1. Biochem Biophys Res Com 257: 218-222
Gessler P, Neu S, Nebe T, Speer CP (1999): Granulocyte colony-stimulating factor receptor expression on neutrophils of term and preterm neonates with and without signs of infection. Eur J Pediatr 158: 497-500
Elmlinger MW, Grund R, Buck M, Wollmann HA, Feist N, Weber MM, Speer CP, Ranke MB (1999): Limited proteolysis of the IGF binding protein-2 (IGFBP-2) by a specific serine protease activity in early breast milk. Pediatr Res 46: 76-81
Schröder A, Herting E, Speer CP (1999) : Aktivität von Superoxiddismutase und Katalase im Tracheobronchialsekret nach Surfactantbehandlung Frühgeborener mit Atemnotsyndrom. Z Geburtsh Neonatol 203: 201-206
Schmidt B, Speer CP (1999) : Spontane intestinale Perforation bei Frühgeborenen. Z Geburtsh Neonatol 203: 261-263
Kramer B, Speer CP (1999) : Die Lungenhypoplasie: eine unterschätzte Diagnose? Z Geburtsh Neonatol 203: 143-151
Maier RF, Obladen M, Speer CP (1999): Erythropoietin and iron therapy for preterm infants. J Pediatr 134(4): 521-522
Haber HP, Bernhardt C, Dammann F, Ruck P, Stuhldreier G, Speer CP (1999): Cystic lymphangioma in an asymptomatic newborn: an uncommon localization in the ileum. J Pediatr Gastroenterol Nutr 28(4): 446-8
Singer, D. (1999):Neonatal tolerance to hypoxia: A comparative-physiological approach. Comp. Biochem. Physiol. A 123, 221-234
